Protection of DNA against low-energy electrons by amino acids: a first-principles molecular dynamics study
نویسندگان
چکیده
منابع مشابه
Protection of DNA against low-energy electrons by amino acids: a first-principles molecular dynamics study.
Using first-principles molecular dynamics simulations, we have investigated the notion that amino acids can play a protective role when DNA is exposed to excess electrons produced by ionizing radiation. In this study we focus on the interaction of glycine with the DNA nucleobase thymine. We studied thymine-glycine dimers and a condensed phase model consisting of one thymine molecule solvated in...
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Today, targeted radiation therapy (TRT) methods for cancer treatment, besides the goal of completely destroying the target tumor, attempts to prevent nearby healthy cells from exposure to ionizing radiation as far as possible. Hence, short-range charged particles, such as low-energy electrons that are suited to achieving these two goals together, play an important role in TRT and so, adoption o...
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ژورنال
عنوان ژورنال: Phys. Chem. Chem. Phys.
سال: 2014
ISSN: 1463-9076,1463-9084
DOI: 10.1039/c4cp03906h